Lymphoma Research
Lymphoma Genomics
Lymphoma is a common cancer that may be divided into numerous sub-types. Our laboratory has focused on using next-generation sequencing to identify somatic genomic alternations (mutations) and changes in RNA expression in lymphoma samples, to better understand the molecular events responsible for lymphoma development, progression, and transformation. We have teamed up with the Griffith Laboratory at The Genome Institute at Washington University, and current projects focus on follicular lymphoma and Hodgkin lymphoma. Lymphoma team collaborators at Washington University include Nancy Bartlett, Amanda Cashen, Brad Kahl, Neha Mehta-Shah, Eric Duncavage.
FUNDING:
The following grants or awards support (or have supported) this research:
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Siteman Cancer Center Research Development Award
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Follicular Lymphoma Pathway Award, Lymphoma Research Foundation
Lymphoma Immunotherapy
We also have an active translational research program advancing novel immunotherapy strategies for patients with lymphoma. These include utilizing cytokines such as IL-15 to augment innate and adaptive immunity against lymphoma, in concert with lymphoma-targeting therapeutic monoclonal antibodies.